Adrenaline - stimulated glycogen breakdown activates glycogen synthase and 1 increases insulin - stimulated glucose uptake in epitrochlearis muscles
نویسندگان
چکیده
4 Department of Physical Performance, Norwegian School of Sports Sciences, P.O.Box 4014 11 Ullevål Stadion, Sognsveien 220, NO-0806 Oslo, Norway 12 13 Running Title: Cori cycle and insulin sensitivity in skeletal muscles 14 15 16 17 Corresponding Author: 18 Jørgen Jensen, Department of Physical Performance, Norwegian School of Sport Sciences, 19 Sognsvann 220, P.O.Box 4014 Ullevål Stadion, 0806 Oslo, Norway 20 Phone: +47 2326 2249 21 Fax: +47 2223 4220 22 E.mail: [email protected] 23 24 25 Articles in PresS. Am J Physiol Endocrinol Metab (December 2, 2014). doi:10.1152/ajpendo.00282.2014
منابع مشابه
Epinephrine-stimulated glycogen breakdown activates glycogen synthase and increases insulin-stimulated glucose uptake in epitrochlearis muscles.
Epinephrine increases glycogen synthase (GS) phosphorylation and decreases GS activity but also stimulates glycogen breakdown, and low glycogen content normally activates GS. To test the hypothesis that glycogen content directly regulates GS phosphorylation, glycogen breakdown was stimulated in condition with decreased GS activation. Saline or epinephrine (0.02 mg/100 g rat) was injected subcut...
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